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Dermosone is a cream with anti-inflammatory, antiallergic and bactericidal properties, for dermatological use. Dermosone Dermal Cream combines the sustained anti-inflammatory, antipruritic and vasoconstrictive effect of betamethasone with the broad-spectrum bactericidal action of neomycin sulfate. Neomycin provides a highly effective topical treatment for primary and secondary bacterial skin infections.

Dermosone Dermal Cream is intended for the treatment of numerous acute and chronic skin conditions of allergic and inflammatory origin with associated bacterial superinfection.


Dermosone is indicated for: Acute and chronic allergic dermatitis, due to exogenous and endogenous causes. Contact dermatitis Childhood eczema and Eczematous dermatitis, Erythematous-exudative skin conditions when complicated with primary and secondary bacterial infections. Pustular acne. Intertrigo. Acute inflammatory and exudative forms


Prolonged topical use of antibiotics may occasionally cause the proliferation of non-susceptible microorganisms. If this occurs or if irritation, hypersensitivity or superinfection occurs with the use of Dermosone Cream, treatment should be discontinued and appropriate therapy initiated.

Any of the side effects associated with systemic corticosteroid use, including adrenal suppression, can also occur with topical corticosteroids, especially in infants and children. Dermosone will be used during pregnancy only if the potential benefit justifies the risk to the fetus.

Use in lactating women: Since it is not known whether topical administration of corticosteroids can lead to sufficient systemic absorption to produce detectable amounts in breast milk, the decision should be made whether to discontinue breast-feeding or to use the drug taking into account the importance of it for the mother.

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Drug interactions

The interactions that can occur with betamethasone correspond to its systemic use. There are no known interactions between topical betamethasone and other drugs. Concurrent use of other neurotoxic and nephrotoxic drugs increases the possibility of side effects of neomycin, including other aminoglycosides or polymyxin. Inhibits the gastrointestinal absorption of penicillin V, as well as vitamin B-12, methotrexate, and 5-fluoruracil. The gastrointestinal absorption of digoxin also appears to be inhibited, so serum digoxin levels should be monitored.

Side effects

Locally there may be irritation, dry skin, folliculitis, hypopigmentation, and skin atrophy due to corticosteroids. Neomycin treatment has produced transient irritation (erythema and pruritus) that usually does not require discontinuation of treatment.

Posology and use


Local application 1 or 2 times a day. Treatment should be continued for a reasonable time after symptoms disappear. When the acuity of the condition indicates so, Dermosona Cream can be applied with a bandage (gauze) to maintain greater contact.

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Each 100g contain:

Betamethasone (Valerato)     0.05g

Neomycin (Sulfate)     0.5g

C.S.P. excipients     100g

Administration route



Box containing tube with 20g of cream.

Storage Recommendations

Store at a temperature of 20 °C to 30 °C.

Contraindications and warnings

Dermosona is contraindicated in case of hypersensitivity to any of the components, tuberculosis or viral skin conditions.



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