Nerodil

Indications

Nerodil is indicated to treat acute inflammatory processes of arthritic, neuritic or non-articular rheumatic origin, such as: bursitis, tendinitis, synovitis, fasceitis, arthritis and radiculitis, sciatic neuralgia, torticollis and trauma.

Properties

Nerodil is a combination of the most important neurotropic factors of the B complex with dexamethasone.

Dexamethasone is one of the most powerful anti-inflammatory steroids known, with the minimum of salt and water retention effects.

It is effectively absorbed when administered orally as dexamethasone base with an availability of 14% – 78% and 2.6% is excreted in the urine. It binds to plasma proteins in 68%, with a half-life of 3-4 hours and a biological half-life of 36 to 54 hours. Due to its increased anti-inflammatory action, dexamethasone blocks inflammatory disorders that occur in neuromuscular disorders. Another outstanding pharmacological characteristic of dexamethasone is its sustained therapeutic action of up to 72 hours duration.

Finally, the neurotropic, antalgic and antineuritic action of vitamins B1, B6 and B12, is associated with the anti-inflammatory action of dexamethasone giving us a product with a powerful therapeutic spectrum.

Contraindications

Viral or bacterial infections, gastric and duodenal ulcer, hypertension, pregnancy, diabetes, systemic mycoses, immuno-suppressed.

Drug interactions

With cardiac glycosides, saluretics, oral antidiabetics, coumarin derivatives, salicylates, rifampicin, adrenaline and L-dopa.

Side effects

Fluid retention, full moon face, hirsutism, irritability.

Composition

Dexamethasone     0.5 mg

Vitamin B1     100 mg

Vitamin B6     100 mg

Vitamin B12     5,000 mcg


Administration route

Oral


Posology

 

1-2 tablets every 8 hours for 5-7 days. After the acute symptoms subside, it is recommended to continue treatment with Dolotrop-K orally for an additional 2-3 weeks.

 


Presentation

Box containing one blister with 10 coated tablets.

          Box containing five blisters with 10 coated tablets.