Cerepens

Pygeum Africanum Extract 50mg / Serenoa Repens 160mg Dry Extract

Pharmacological Properties

Pygeum Africanum

The extract of pygeum africanum has antiproliferative effects on fibroblasts stimulated by b-FGF (basic-Fibroblast Growth Factor) in benign prostatic hyperplasia. Furthermore, the extract of pygeum africanum does not interfere with the hormonal activity of the male genital sphere.

Serenoa Repens

The purified serenoa repens extract has antiandrogenic properties that are specifically exerted at the target organ level without any other hormonal incidence or interference with the hypothalamic-pituitary axis. These antiandrogenic properties are explained by an inhibition of DHT synthesis and its binding to its cytosolic receptor. Translocation of the hormone becoming impossible in the nucleus must result in a decrease in protein synthesis. Such a decrease in protein synthesis was evidenced by a hormonal association of testosterone and prolactin. On the other hand, serenoa repens, by mediating the inhibition of phospholipase A2 activity and the release of arachidonic acid, is capable of decreasing the synthesis of prostaglandins involved in the tone and motility of the lower urinary tract walls. , as well as in the hormonal interactions that play a preponderant role in the origin of hyperplasia and prostatic inflammation. Pharmacology also highlights an important decongestant effect of Cerepens that is very evident in the vascular phases of inflammation with reduced capillary permeability.

This activity is particularly interesting in the course of evolutionary access and in the pelvic congestion factor, taking a preponderant importance in the determination of the symptoms. These antiandrogenic and decongestant effects could explain the results observed in the symptoms of benign prostatic hypertrophy.


Indications

  • Treatment of prostatic hypertrophy in its initial phase.
  • Prostatic congestion.
  • Acute and chronic prostatitis and vesiculitis.
  • Pre and post-operative treatment of prostatectomy.
  • Prostatic urinary obstruction (decreased urinary volume and strength).
  • Prostatic lengthening.

Posology

 

2 capsules daily by mouth, one in the morning and one at night during meals. Taking Cerepens on an empty stomach can sometimes cause nausea.

Cerepens is indicated for long-term treatment due to its wide margin of safety.

Incompatibilities

It lacks them and can be associated with any other antibiotic, hormonal, anti-sclerosis medication, etc.

Composition

Each capsule contains:

Serenoa repens dry extract     160 mg

Pygeum africanum     50 mg

C.S.P. excipients     1 capsule


Administration route

Oral


Presentation

Box containing three blisters with 10 capsules each.


Storage Recommendations

Store below 30 °C.


Contraindications

Cerepens is contraindicated in patients with hypersensitivity to the components of the product.